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. 2019 Oct 16;18(6):4329–4339. doi: 10.3892/etm.2019.8108

Figure 4.

Figure 4.

Histological analysis of haematoxylin and eosin stained rat heart tissues of control, Fe2O3NP-exposed group, AgNP-exposed group, and Fe2O3NP and AgNP-coexposed group. (A) Control rats demonstrated normal myofiber cells and normal architecture. (B) Heart tissues of Fe2O3NP-exposed group revealed myocardial degeneration changes. (C) Heart of AgNP-exposed group revealed fragmentation of sacroplasm and degeneration changes in myocardial fibers. (D) Heart of the Fe2O3NP and AgNP-coexposed group revealed loss of cross striation and severe myocardial degeneration changes (magnification, ×400). Fe2O3NP, iron oxide nanoparticle; AgNP, silver nanoparticle.