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. 2019 Oct 25;20(21):5322. doi: 10.3390/ijms20215322

Table 1.

Deregulated miRNAs in selected in vitro studies in endometriosis.

References Main Biological Function Promoted Experimental Design Main Deregulated miRNAs in Patients
[49] Cell survival OMA cell line under hypoxia ↑ miR-210
[51] Invasiveness Immortalized endometriotic cell line 12Z, the stromal cell line ST-T1b and primary endometriotic stromal cells ↓ miR-200b
[52] Primary eutopic and control stromal cells ↓ miR-183
[53] Primary ectopic, eutopic and control stromal cells ↓ miR-199a
[54] Proliferation Primary ectopic and control stromal cells ↑ miR-210
[51] Immortalized endometriotic cell line 12Z, the stromal cell line ST-T1b and primary endometriotic stromal cells ↓ miR-200b
[55] Ectopic endometrial cells ↓ miR-2861
[56] Primary ectopic, eutopic and control stromal cells ↓ miR-195
[57] Primary ectopic and control stromal cells ↓ mi-196b
[58] Apoptosis evasion Endometrial cell lines ↑ miR-181c
[59] Ectopic endometrial stromal cells ↓ miR-143-3p
[55] Ectopic endometrial cells ↓ miR-2861
[56] Primary ectopic, eutopic and control stromal cells ↓ miR-195
[57] Primary ectopic and control stromal cells ↓ mi-196b
[49]
[54]
OMA cell line under hypoxia
Primary ectopic and control stromal cells
↑ miR-210
[60] Angiogenesis Primary ectopic, eutopic and control stromal cells ↓ miR-16, ↓ miR-29c-3p, ↓ miR-424

↑, up-regulated levels; ↓ down-regulated levels; OMA: ovarian endometrioma.