Table 1.
References | Main Biological Function Promoted | Experimental Design | Main Deregulated miRNAs in Patients |
---|---|---|---|
[49] | Cell survival | OMA cell line under hypoxia | ↑ miR-210 |
[51] | Invasiveness | Immortalized endometriotic cell line 12Z, the stromal cell line ST-T1b and primary endometriotic stromal cells | ↓ miR-200b |
[52] | Primary eutopic and control stromal cells | ↓ miR-183 | |
[53] | Primary ectopic, eutopic and control stromal cells | ↓ miR-199a | |
[54] | Proliferation | Primary ectopic and control stromal cells | ↑ miR-210 |
[51] | Immortalized endometriotic cell line 12Z, the stromal cell line ST-T1b and primary endometriotic stromal cells | ↓ miR-200b | |
[55] | Ectopic endometrial cells | ↓ miR-2861 | |
[56] | Primary ectopic, eutopic and control stromal cells | ↓ miR-195 | |
[57] | Primary ectopic and control stromal cells | ↓ mi-196b | |
[58] | Apoptosis evasion | Endometrial cell lines | ↑ miR-181c |
[59] | Ectopic endometrial stromal cells | ↓ miR-143-3p | |
[55] | Ectopic endometrial cells | ↓ miR-2861 | |
[56] | Primary ectopic, eutopic and control stromal cells | ↓ miR-195 | |
[57] | Primary ectopic and control stromal cells | ↓ mi-196b | |
[49] [54] |
OMA cell line under hypoxia Primary ectopic and control stromal cells |
↑ miR-210 | |
[60] | Angiogenesis | Primary ectopic, eutopic and control stromal cells | ↓ miR-16, ↓ miR-29c-3p, ↓ miR-424 |
↑, up-regulated levels; ↓ down-regulated levels; OMA: ovarian endometrioma.