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. 2019 Nov-Dec;64(6):423–430. doi: 10.4103/ijd.IJD_353_18

Table 4.

Determinants of drug reactions

Cumulative dose of the drug
Route of administration
Preexisting genetic/medical illnesses
Pharmacologic properties of the drug
Age and gender
Drug-drug interactions
History of allergies to drugs
Idiosyncrasy