Figure 2.

Effects of velusetrag on contextual fear extinction in mice. Mice were given an intraperitoneal injection of velusetrag at a single dose of 3.0 mg/kg in saline containing 1% DMSO or the vehicle only 2 h prior to both extinction training sessions. The data of the control + vehicle and MPTP + vehicle are the same data shown in Figure 1. Data are expressed as the mean ± SEM; n = 7–8. ** p < 0.01 vs. control + vehicle on each day, ⁺⁺ p < 0.01 vs. MPTP + vehicle on each day, ^# p < 0.05 and ^## p < 0.01 vs. control + velusetrag on each day (one-way ANOVA followed by Tukey’s post-hoc test).