Effect of LINC00152 knockdown on apoptosis. At 24 h post-transfection with si-1-LINC00152 or si-NC, (A and B) COC1 and (C and D) COC1/DDP cells were treated with 4 or 32 µg/ml cisplatin, respectively. After 24 h of cisplatin treatment, apoptosis was analyzed by flow cytometry. ***P<0.001 vs. si-NC (0 µg/ml cisplatin); ###P<0.001 vs. si-1-LINC00152 (4 or 32 µg/ml cisplatin); ΔP<0.05 and ΔΔΔP<0.001 vs. si-NC (4 or 32 µg/ml cisplatin). si, small interfering RNA; NC, negative control; FITC, fluorescein isothiocyanate.