Figure 2.

Mitochondrial oxidative phosphorylation capacity is comprised of both number and function that can be measured in vivo or in vitro. Mitochondria within skeletal muscle measured in vivo can be measured via phosphorus magnetic resonance spectroscopy (³¹PMRS). ³¹PMRS infers function from measures of mitochondrial oxidative phosphorylation (MOP) capacity, that when paired with V_MITO quantitatively describes function. Mitochondrial function in vitro can be measured via high-resolution respirometry following isolation of the organelle from the tissue. Created with Biorender.com.