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. 2019 Oct 14;18(6):4273–4286. doi: 10.3892/etm.2019.8101

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Copyright: © Dong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — GAS1 promotes SF apoptosis. (A) Representative flow cytometry dot plots of (Aa) the blank control group, and non-OASFs transfected with (Ab) pcDNA-vector, (Ac) pcDNA-GAS1, (Ad) siRNA-NC, (Ae) siRNA-GAS1 and (Af) siRNA-GAS1 + LY treatment. (B) Quantified data and corresponding statistical analysis of early- and end-stage apoptotic cells from each of the aforementioned groups. *P<0.01 and **P<0.001. PE, phycoerythrin; APC, allophycocyanin; SF, synovial fibroblasts; OASFs, osteoarthritis synovial fibroblasts; GAS1, growth arrest specific-1; NC, negative control; siRNA, small interfering RNA; LY, LY294002.