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. 2019 Nov 5;20(21):5509. doi: 10.3390/ijms20215509

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Physiological underpinnings of key imaging modalities for BAT research. The physiological basis for key imaging modalities in brown adipose tissue (BAT) research includes changes in inner action, vascularity, fat fraction, mitochondrial activity and key substrate transport and utilization. Comparison is made to white adipose tissue (WAT). N: nucleus, M: mitochondria, L: lipid droplet, FDG: ¹⁸F-Fluorodeoxyglucose, FTHA: ¹⁸F-Fluoro-6-Thia-Heptadecanoic Acid, BMIPP: ¹²³I-Beta-Methyl-Iodophenyl-Pentadecanoic Acid.