Table 3.
FuTAGs located in all chromosomes and upregulated (FC > 1.5) in CRC in comparison to normal mucosa. Data obtained by HTA 2.0.
| Transcript Cluster ID | FC > 1.5 (CRCvs.MU) GSE73360 and GSE84984 [66,67,68] |
FDR p-Value (CRC VS. MU) | Chr Position | Gene Symbol | Description (Contain Readthrough Word) |
FuTAG Reported in Table 1 |
|---|---|---|---|---|---|---|
| TC02005002.hg.1 | 1.57 | 2 × 10−6 | 2q31.1 | KLHL23; PHOSPHO2-KLHL23 | kelch-like family member 23; PHOSPHO2-KLHL23 readthrough; NULL | [57] |
| TC02005005.hg.1 | 2 | 1.7 × 10−7 | 2q33.1 | MOB4; HSPE1-MOB4 | MOB family member 4, phocein; HSPE1-MOB4 readthrough; NULL | |
| TC02002467.hg.1 | 2.32 | 2 × 10−6 | 2q24.2 | LY75-CD302; CD302; LY75 | LY75-CD302 readthrough; CD302 molecule; lymphocyte antigen 75; NULL | [51] |
| TC05000726.hg.1 | 2.61 | 1.2 × 10−7 | 5q31.3 | EIF4EBP3; ANKHD1; ANKHD1-EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3; ankyrin repeat and KH domain containing 1; ANKHD1-EIF4EBP3 readthrough; NULL | [58] |
| TC05001690.hg.1 | 1.67 | 2 × 10−6 | 5q22.3 | TMED7-TICAM2; TICAM2; TMED7 | TMED7-TICAM2 readthrough; toll-like receptor adaptor molecule 2; transmembrane emp24 protein transport domain containing 7; NULL | [69] |
| TC07003311.hg.1 | 1.75 | 1.4 × 10−5 | 7q11.23 | DTX2P1-UPK3BP1-PMS2P11; LOC100132832 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene; PMS2 postmeiotic segregation increased 2 (S. cerevisiae) pseudogene | |
| TC0X002317.hg.1 | 1.64 | 1 × 10−10 | Xq22.1 | RPL36A; RPL36A-HNRNPH2 | ribosomal protein L36a; RPL36A-HNRNPH2 readthrough; NULL | |
| TC0X002316.hg.1 | 4.2 | 4.1 × 10−12 | Xq22.1 | HNRNPH2; RPL36A-HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H’); RPL36A-HNRNPH2 readthrough; NULL | |
| TC10002935.hg.1 | 2.17 | 5.4 × 10−9 | 10p12.2 | BMI1; COMMD3-BMI1 | BMI1 polycomb ring finger oncogene; COMMD3-BMI1 readthrough; NULL | |
| TC11000477.hg.1 | 2.26 | 1.7 × 10−8 | 11q12.1 | CNTF; ZFP91; ZFP91-CNTF | ciliary neurotrophic factor; ZFP91 zinc finger protein; ZFP91-CNTF readthrough (NMD candidate); zinc finger protein 91 homolog (mouse); ZFP91-CNTF readthrough (non-protein coding); NULL | |
| TC11000673.hg.1 | 1.58 | 6.5 × 10−13 | 11q13.2 | RBM14; RBM4; RBM14-RBM4; LOC101059993 | RNA binding motif protein 14; RNA binding motif protein 4; RBM14-RBM4 readthrough; uncharacterized LOC101059993; NULL | |
| TC11002132.hg.1 | 1.72 | 7.6 × 10−8 | 11q14.1 | NDUFC2-KCTD14; NDUFC2; KCTD14 | NDUFC2-KCTD14 readthrough; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa; potassium channel tetramerisation domain containing 14; NULL | |
| TC12001797.hg.1 | 3.66 | 1.9 × 10−12 | 12q21.33 | POC1B; POC1B-GALNT4; GALNT4 | POC1 centriolar protein homolog B (Chlamydomonas); POC1B-GALNT4 readthrough; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) | |
| TC13001721.hg.1 | 1.7 | 8.3 × 10−9 | 13q33.1 | ERCC5; BIVM-ERCC5 | excision repair cross-complementing rodent repair deficiency, complementation group 5; BIVM-ERCC5 readthrough; NULL | |
| TC14001267.hg.1 | 2.85 | 5.9 × 10−10 | 14q24.2 | SYNJ2BP-COX16; COX16; SYNJ2BP | SYNJ2BP-COX16 readthrough; COX16 cytochrome c oxidase assembly homolog (S. cerevisiae); synaptojanin 2 binding protein | |
| TC17000082.hg.1 | 1.83 | 3 × 10−11 | 17p13.1 | RNASEK; C17orf49; RNASEK-C17orf49 | ribonuclease, RNase K; chromosome 17 open reading frame 49; RNASEK-C17orf49 readthrough | |
| TC17002881.hg.1 | 1.74 | 1 × 10−10 | 17q21.33 | NME2; NME1-NME2 | NME/NM23 nucleoside diphosphate kinase 2; NME1-NME2 readthrough; NULL | |
| TC18001003.hg.1 | 9.48 | 3 × 10−10 | 18q21.1 | SNORD58B; RPL17; RPL17-C18orf32 | small nucleolar RNA, C/D box 58B; ribosomal protein L17; RPL17-C18orf32 readthrough | |
| TC20001752.hg.1 | 1.72 | 4.3 × 10−9 | 20q13.13 | TMEM189; TMEM189-UBE2V1; UBE2V1 | transmembrane protein 189; TMEM189-UBE2V1 readthrough; ubiquitin-conjugating enzyme E2 variant 1; NULL | [17] |
| TC6_apd_hap1000079.hg.1 | 4.49 | 1.8 × 10−13 | 6p21.33 | DDX39B; ATP6V1G2-DDX39B; OTTHUMG00000148789; BAT1 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; ATP6V1G2-DDX39B readthrough (NMD candidate); NULL |