Table 4.
β-Secretase inhibitory activity of compounds 2b, 2f, 3b, 3d and 3f.
| Compound | IC50 (µM) BACE-1 |
|---|---|
| 2b | 21.6 ± 0.01 |
| 2f | 15.4 ± 0.02 |
| 3b | 17.3 ± 0.03 |
| 3d | 32.8 ± 0.02 |
| 3f | 25.3 ± 0.04 |
| Quercetin | 12.5 ± 0.01 |
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