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. Author manuscript; available in PMC: 2020 Oct 18.
Published in final edited form as: ACS Chem Biol. 2019 Sep 19;14(10):2176–2184. doi: 10.1021/acschembio.9b00381

Figure 2.

Figure 2.

(a) Flow cytometry analysis of anti-MUC1 IgG antibodies showed Qβ-MUC1-Tf 17 elicited antibodies with significantly stronger binding to tumor cells compared with Qβ-MUC1-Tn elicited antibodies. Binding to B16-MUC1 cells was tested with 1:20 dilution of the corresponding sera, (b) Antibodies induced by Qβ-MUC1 conjugates exhibited significantly high CDC toward tumor cells. CDC toward B16-MUC1 cells was determined by a MTS assay. Each symbol represents one mouse (n = 5 mice for each group); *p < 0.05, **p < 0.01. The p values were determined through a two-tailed unpaired Student’s t-test using GraphPad Prism.