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. Author manuscript; available in PMC: 2019 Nov 19.
Published in final edited form as: Ann Intern Med. 2017 Jan 17;166(6):401–411. doi: 10.7326/M16-1245

Table 3.

Estimated Baseline Means, Mean Changes From Baseline to 6 Months and Baseline to12 Months, and Difference of Mean Changes Between Each Intervention Group and Usual Care and Associated 95% CIs*

Outcome Mean
Baseline
Baseline to 6-Mo
Difference
(95% CI)
Baseline to
12-Mo Difference
(95% CI)
Difference in Baseline
to 12 Mo vs. Usual Care
(95% CI)
P Value

WOMAC score
 Total
  Usual care 35.8 −6.2 (−8.6 to −3.9) −6.1 (−8.6 to −3.7) -
  Patient 41.1 −7.3 (−9.8 to −4.8) −7.7 (−10.3 to −5.1) −1.5 (−5.1 to 2.0) 0.40
  Provider 37.6 −5.0 (−7.3 to −2.8) −3.7 (−6.0 to −1.3)   2.5 (−0.9 to 5.9) 0.152
  Patient-provider 39.8 −8.9 (−11.3 to −6.6) −6.8 (−9.4 to −4.3) −0.7 (−4.2 to 2.8) 0.69
 Pain subscale
  Usual care   7.6 −1.5 (−2.1 to −0.9) −1.0 (−1.7 to −0.4) -
  Patient   8.8 −1.9 (−2.5 to −1.2) −1.5 (−2.2 to −0.8) −0.4 (−1.4 to 0.5) 0.37
  Provider   8.0 −1.3 (−1.9 to −0.7) −0.8 (−1.4 to −0.1)   0.3 (−0.7 to 1.2) 0.60
  Patient-provider   8.4 −2.2 (−2.8 to −1.5) −1.4 (−2.1 to −0.7) −0.3 (−1.3 to 0.6) 0.49
 Function
  Usual care 24.7 −4.3 (−6.1 to −2.6) −4.6 (−6.3 to −2.8) -
  Patient 28.5 −5.0 (−6.8 to −3.1) −5.6 (−7.4 to −3.7) −1.0 (−3.5 to 1.6) 0.45
  Provider 26.0 −3.3 (−5.0 to −1.6) −2.3 (−4.0 to −0.6)   2.3 (−0.1 to 4.7) 0.065
  Patient-provider 27.5 −6.1 (−7.9 to −4.3) −4.8 (−6.6 to −3.0) −0.2 (−2.7 to 2.3) 0.88
PHQ-8 score
 Usual care   4.0 NA −0.7 (−1.3 to −0.1) -
 Patient   4.8 NA −0.4 (−1.0 to 0.2)   0.3 (−0.6 to 1.2) 0.55
 Provider   4.5 NA      0 (−0.6 to 0.5)   0.6 (−0.2 to 1.5) 0.136
 Patient-provider   4.9 NA −0.6 (−1.2 to 0)   0.1 (−0.8 to 1.0) 0.86
Physical function (SPPB score)§
 Usual care   8.5 NA      0 (−0.4 to 0.3) -
 Patient   8.3 NA −0.3 (−0.7 to 0.1) −0.3 (−0.8 to 0.3) 0.32
 Provider   8.8 NA −0.5 (−0.8 to −0.1) −0.4 (−1.0 to 0.1) 0.092
 Patient-provider   8.5 NA −0.3 (−0.7 to 0.1) −0.3 (−0.8 to 0.3) 0.34
BMI, kg/m2||
 Usual care 35.6 NA −0.1 (−0.3 to 0.5) -
 Patient 35.0 NA −0.5 (−0.9 to 0) −0.6 (−1.2 to 0.1) 0.073
 Provider 36.3 NA −0.6 (−1.0 to −0.2) −0.7 (−1.2 to −0.1) 0.022
 Patient-provider 35.3 NA −0.4 (−0.9 to 0) −0.6 (−1.1 to 0) 0.069
Change from baseline in weekly frequency of all exercise measured by mean CHAMPS scored
 Usual care 15.3 NA −1.2 (−2.7 to 0.2) -
 Patient 14.9 NA −0.7 (−2.2 to 0.8)   0.5 (−1.3 to 2.3) 0.58
 Provider 14.8 NA −1.5 (−2.9 to −0.1) −0.3 (−2.3 to 1.7) 0.73
 Patient-provider 12.7 NA   0.6 (−0.9 to 2.1)   1.8 (−0.3 to 3.9) 0.087
Change from baseline in weekly duration of all exercise measured by mean CHAMPS score, h/wk
 Usual care 12.2 NA −0.6 (−2.1 to 1.0) -
 Patient 13.7 NA −0.7 (−2 to 3 to 0.6) −0.1 (−2.0 to 1.7) 0.76
 Provider 12.4 NA −0.9 (−2.4 to 0.6) −0.3 (−2.5 to 1.9) 0.89
 Patient-provider 10.8 NA −0.4 (−2.0 to 1.2)   0.1 (−2.1 to 2.4) 0.90

BMI = body mass index; CHAMPS = Community Healthy Activities Model Program for Seniors; NA = not available; PHQ-8 = 8-item Patient Health Questionnaire; SPPB = Short Physical Performance Battery; WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index.

*

Calculated by hierarchical linear mixed models fit using PROC MIXED (SAS Institute). Follow-up data at 6 mo are missing for 69 participants (25 in the patient-provider group, 26 in the patient group, 11 in the provider group, and 7 in the usual care group) and at 12 mo for 102 participants (37 in the patient-provider group, 31 in the patient group, 16 in the provider group, and 18 in the usual care group).

Data for the total and physical function scores are missing for 3 participants (1 at baseline, 1 in the patient group at 6 mo, and 1 in the provider group at 12 mo).

Data are missing for 13 participants (2 at baseline, 3 in the patient-provider group, 3 in the patient group, 2 in the provider group, and 3 in the usual care group at 12 mo).

§

Data are missing for 65 participants (15 at baseline, 11 in the patient-provider group, 11 in the patient group, 17 in the provider group, and 11 in the usual care group at 12 mo).

||

Data are missing for 48 participants (11 in the patient-provider group, 10 in the patient group, 16 in the provider group, and 11 in the usual care group at 12 mo).

Data for frequency and duration of exercise are missing for 10 participants (2 in the patient-provider group, 3 in the patient group, 2 in the provider group, and 3 in the usual care group at 12 mo). Mean baseline CHAMPS scores are observed, because outcome in models was changed from baseline to 12 mo. Only patients with nonmissing change scores were included in the observed baseline CHAMPS score means.