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. Author manuscript; available in PMC: 2019 Nov 19.
Published in final edited form as: Nat Protoc. 2019 Feb 1;14(3):756–780. doi: 10.1038/s41596-018-0113-7
-gene_summary Either a file or a data frame whose column name contains ‘Gene’, ‘dmso.beta’ and ‘plx.beta’ which corresponding to the parameters -ctrlname and -treatname. In this specific MAGeCK MLE result (from Dataset 2, generated in Step 7Avii), ‘dmso.beta’ and ‘plx.beta’ correspond to the control (DMSO) and drug treatment conditions (PLX), respectively.
-ctrlname A character vector, specifying the name of control samples.
-treatname A character vector, specifying the name of treatment samples.
-organism A character, specifying an organism, such as “hsa” or “Human”(default), and “mmu” or “Mouse”.
-prefix A character, indicating the prefix of output file name.
-pathway_limit A two-length vector (default: c(3, 50)), specifying the minimal and maximal size of gene sets for enrichent analysis.