Table 5.

Multivariate analysis of variables correlated with the treatment regimen status and other significant prognostic factors in 730 eligible cases

	DMFS			LRFS			PFS			OS
	B	HR(95%CI)	P	B	HR (95%CI)	P	B	HR (95%CI)	P	B	HR (95%CI)	P
Gender
Female	1			1			1			1
Male	−0.934	0.393 (0.188–0.823)	0.013	0.247	1.280 (0.733–2.237)	0.385	−0.205	0.815 (0.549–1.210)	0.310	−0.523	0.592 (0.347–1.011)	0.055
Age
<44	1			1			1			1
≥ 44	−0.096	0.909 (0.582–1.421)	0.675	−0.439	0.645 (0.393–1.058)	0.082	−0.256	0.774 (0.571–1.050)	0.100	−0.252	0.777 (0.534–1.132)	0.189
Tumor stage
T1	1			1			1			1
T2	0.149	1.161 (0.335–4.026)	0.814	−0.229	0.795 (0.113–5.603)	0.818	−0.200	0.819 (0.287–2.339)	0.709	0.206	1.229 (0.407–3.714)	0.715
T3	−0.894	0.409 (0.128–1.305)	0.131	0.109	1.116 (0.246–5.065)	0.887	−0.510	0.600 (0.256–1.405)	0.240	−0.546	0.580 (0.215–1.561)	0.280
T4	−0.474	0.623 (0.248–1.562)	0.313	−0.329	0.720(0.175–2.954)	0.648	−0.664	0.515 (0.243–1.091)	0.083	−0.632	0.531 (0.231–1.223)	0.137
Node stage
N0	1			1			1			1
N1	−1.979	0.138 (0.046–0.418)	< 0.001	−1.437	0.238 (0.047–1.210)	0.083	−1.603	0.201 (0.088–0.458)	< 0.001	−1.509	0.221 (0.086–0.567)	0.002
N2	−2.251	0.105 (0.043–0.260)	< 0.001	−0.594	0.552 (0.160–1.902)	0.347	−1.329	0.265 (0.138–0.508)	< 0.001	−1.242	0.289 (0.141–0.594)	0.001
N3	−1.330	0.264 (0.111–0.629)	0.003	−0.329	0.720(0.204–2.542)	0.609	−0.876	0.416 (0.216–0.804)	0.009	−0.800	0.449 (0.216–0.934)	0.032
Clinical stage
III	1			1			1			1
IV	0.224	1.251 (0.436–3.593)	0.677	−0.052	0.950 (0.212–4.254)	0.946	0.080	1.083 (0.482–2.434)	0.847	−0.448	0.639 (0.256–1.598)	0.338
Target therapy
Without	1			1			1			1
With	0.840	2.317 (1.224–4.384)	0.010	−0.339	0.712 (0.427–1.189)	0.194	0.353	1.423 (0.985–2.058)	0.060	0.754	2.125 (1.269–3.560)	0.004
Induction chemotherapy
No	1			1			1			1
Yes	0.303	1.354 (0.849–2.159)	0.203	−0.209	0.811 (0.471–1.398)	0.451	0.031	1.031 (0.742–1.434)	0.855	−0.012	0.988 (0.655–1.490)	0.955