Table 1.
Maternal and pregnancy characteristics of the women (n = 943) diagnosed with fetal ventriculomegaly by prenatal ultrasonography.
| Characteristic | All cases n = 943 | Isolated cases n = 349 | Non-isolated cases n = 594 | Statistical significancea |
|---|---|---|---|---|
| Maternal age, years | 29.8 ± 5.1 | 27.9 ± 4.2 | 29.6 ± 5.5 | P = 1.9 × 10−6 |
| Gestational age, weeks | ||||
| At first diagnosis | 23.8 ± 8.2 | 24.3 ± 8.5 | 23.4 ± 8.1 | NS |
| At delivery (live births) | 37.0 ± 5.1 | 37.2 ± 4.9 | 36.6 ± 5.5 | NS |
| Side, n, %, (95% CI) | P = 0.005 | |||
| Unilateral | 447, 47.4, (44.2, 50.7) | 186, 53.3, (48.1, 58.5) | 261, 43.9, (40.1, 48.3) | |
| Bilateral | 496, 52.6, (49.3, 55.8) | 163, 46.7, (41.5, 51.9) | 333, 56.1, (51.7, 59.9) | |
| Atrium measurement, n, %, (95% CI) | P = 2.3 × 10−5 | |||
| Mild, 10–12 mm | 768, 81.4, (79.0, 83.9) | 304, 87.1, (83.1, 90.5) | 464, 78.1, (74.7, 81.5) | |
| Moderate, 13–15 mm | 86, 9.1, (7.2, 11.0) | 32, 9.2, (6.3, 12.3) | 54, 9.1, (6.9, 11.4) | |
| Severe, ≥15 mm | 89, 9.4, (7.7, 11.3) | 13, 3.7, (2.0, 5.7) | 76, 12.8, (10.1, 15.7) | |
| Pregnancy outcome, n, %, (95% CI) | ||||
| Missing data | 236 | 102 | 134 | P = 1.6 × 10−11 |
| Late miscarriage | 4, 0.6, (0.0, 1.1) | 1, 0.4, (0.0, 1.2) | 3, 0.7, (0.0, 1.5) | |
| Termination of pregnancy | 202, 28.6, (25.3, 32.0) | 31, 12.6, (8.5, 17.0) | 171, 37.2, (32.8, 41.3) | |
| Stillbirth | 6, 0.8, (0.3, 1.6) | – | 6, 1.3, (0.4, 2.4) | |
| Live birth | 495, 70.0, (66.5, 73.4) | 215, 87.0, (82.6, 91.1) | 280, 60.9, (56.5, 65.2) | |
| About live births, n = 495 | ||||
| Model of delivery, n, %, (95% CI) | P = 2.4 × 10−4 | |||
| Vaginal | 307, 62.0, (57.6, 66.1) | 153, 71.2, (64.7, 76.7) | 154, 55.0, (49.3, 60.7) | |
| Caesarean | 188, 38.0, (33.9, 42.4) | 62, 28.8, (23.3, 35.3) | 126, 45.0, (39.3, 50.7) | |
| Fetal sex ratio, male: female | 2.1:1 | 2.1:1 | 2.1:1 | NS |
| Birth weight, kg | 3.2 ± 0.5 | 3.2 ± 0.4 | 3.1 ± 0.5 | NS |
Data presented as mean ± SD or n of patients, %, (95% confidence interval [CI]).
aIsolated group versus non-isolated ventriculomegaly group; χ2-test or one-way analysis of variance; NS, no significant between-group difference (P ≥0.05).