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PARP-1 inhibitors in clinical development that may be repurposed for wound healing
| PARP Inhibitor | Target PARP |
|---|---|
| Talazoparib (BMN-673)—most potent | PARP-1/2 |
| Veliparib (ABT-888) | PARP-1/2 |
| Rucaparib (AG-014699. CO-338) | PARP-1/2 |
| Olaparib (AZD-2281) | PARP-1/2/3 |
| CEP-9722 | PARP-1/2 |
| Niraparib (MK-4827) | PARP-1/2 |
PARP, polyadenosine diphosphate (ADP)-ribose polymerase.
