Table 3.
Relation of lesion location with various clinical profiles
| Lesion location, mean (SD) | ANOVA | |||||
|---|---|---|---|---|---|---|
| Area A (n=74) | Area B (n=28) | Area C (n=23) | Area D (n=17) | F | P | |
| Age (years) | 68.46 (7.753) | 66.79 (6.641) | 67.35 (7.030) | 67.12 (5.566) | 0.473 | 0.702 |
| Years of education | 9.64 (5.877) | 8.86 (5.407) | 9.70 (5.764) | 9.71 (4.593) | 0.153 | 0.928 |
| Time since stroke (months) | 13.31 (8.158) | 15.62 (10.171) | 14.23 (12.356) | 15.71 (7.389) | 0.547 | 0.651 |
| GAF | 74.42 (6.857) | 73.32 (7.318) | 72.57 (5.017) | 70.65 (6.133) | 1.689 | 0.172 |
| AES (C) | 32.85 (8.551) | 34.50 (10.423) | 38.70 (7.945) | 36.71 (8.498) | 2.925 | 0.036* |
| BPRS | 12.70 (4.742) | 15.64 (4.490) | 12.48 (5.125) | 17.35 (6.623) | 5.827 | 0.001* |
| PSDRS total | 16.84 (5.075) | 19.25 (6.108) | 16.09 (6.338) | 19.53 (6.663) | 2.403 | 0.070 |
| PSDRS mood | 2.00 (0.549) | 2.21 (0.833) | 1.91 (0.733) | 2.24 (.831) | 1.410 | 0.242 |
| PSDRS guilt | 1.24 (0.824) | 1.75 (1.076) | 1.13 (0.757) | 1.53 (.624) | 3.214 | 0.025* |
| PSDRS suicidality | 0.88 (0.618) | 1.25 (0.752) | 1.04 (0.638) | 1.18 (.728) | 2.573 | 0.057 |
| PSDRS sleep | 1.27 (0.556) | 1.57 (0.690) | 1.39 (0.656) | 1.59 (.795) | 2.214 | 0.089 |
| PSDRS appetite | 0.97 (0.596) | 1.07 (0.604) | 0.87 (0.548) | 1.18 (.529) | 1.097 | 0.353 |
| PSDRS apathy | 2.74 (1.481) | 3.07 (1.609) | 2.52 (1.620) | 2.71 (1.532) | 0.578 | 0.631 |
| PSDRS anxiety | 2.04 (1.091) | 2.18 (1.188) | 1.83 (1.114) | 2.71 (1.687) | 1.948 | 0.125 |
| PSDRS catastrophic reaction | 0.95 (0.639) | 1.11 (0.832) | 0.87 (0.626) | 1.47 (1.007) | 2.875 | 0.039* |
| PSDRS emotional dyscontrol | 1.05 (0.402) | 1.14 (0.591) | 1.09 (0.515) | 1.53 (.874) | 3.729 | 0.013* |
| PSDRS anhedonia | 3.69 (1.146) | 3.89 (1.315) | 3.43 (1.273) | 3.41 (1.228) | 0.862 | 0.462 |
| PSDRS diurnal variation | 1.74 (0.812) | 1.64 (0.826) | 1.91 (0.793) | 1.76 (1.033) | 0.443 | 0.723 |
*P<0.05. Area A – Basal ganglia; Area B – Parietal lobe and rest of the MCA territory; Area – Brain stem, cerebellum, and thalamus; Area D – Others (diffuse lesions, frontal lobe, occipital lobe, periventricular region, etc.). PSDRS – Poststroke Depression Rating Scale; AES (C) – Apathy Evaluation Scale (clinician version); GAF – Global Assessment of Functioning Scale; BPRS – Brief Psychiatric Rating Scale; ANOVA – Analysis of variance; SD – Standard deviation