Table 2.

Overview of key changes in the 2018 update of the WHO rabies vaccine position paper.

Topic	2010 position paper	2018 position paper
PEP regimen duration	3–4 weeks 4–5 visits	1–2 weeks 3–4 visits
PrEP regimen duration	3–4 weeks 3 visits	1 week 2 visits
Vaccine dose PEP	ID: 0.8 ml IM: 5 ml	ID: 0.6 ml IM: 4 ml
RIG infiltration mode	Full calculated volume in and around wound. Residual volume IM, at distant site.	In and around wound only, up to maximum calculated volume. No IM administration.
RIG allocation	All category III exposures	High risk category III exposures