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. 2019 Nov 10;25:8472–8481. doi: 10.12659/MSM.918252

Figure 3.

Figure 3

AB23A decreases inflammatory cells infiltration in myocardial tissue and attenuates inflammatory mediator expression in serum of lipopolysaccharide (LPS)-induced mouse sepsis model (A) Inflammatory cells infiltration in myocardial tissue by hematoxylin and eosin (H&E) staining. (B) Concentrations of tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-1β were increased by LPS stimulation and reduced by AB23A treatment (10 mg/kg, 20 mg/kg, 40 mg/kg). *** P<0.001 versus control group. # P<0.05 versus model group. ## P<0.01 versus model group. ### P<0.001 versus model group.