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. Author manuscript; available in PMC: 2019 Nov 19.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Apr 22;500(3):717–722. doi: 10.1016/j.bbrc.2018.04.142

Fig. 2. HCV-HIV co-infection in primary human hepatocytes.

Fig. 2.

Primary hepatocytes were plated on PDMS gels coated with (PDAC/SPS)10 PEM films with 2 kPa (soft) and 24 kPa (stiff) stiffness mimicking healthy and fibrotic liver environment and infected with HCV and HIV, in the presence or absence of pan-caspase inhibitor and AZT. A. HCV RNA (RT-PCR); B. gag HIV RNA (RT-PCR); C. M30 levels in hepatocyte supernatants (fold change, ELISA). All data were generated from 3 independent duplicate experiments and presented as Mean ± SEM. Bars with different letters are significantly different at p ≤ 0.05.