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. 2019 Nov 12;10:830. doi: 10.3389/fpsyt.2019.00830

Table 2.

Distribution of DRD3, COMT, and 5HT2A polymorphisms in youth-onset schizophrenia and control groups.

rs Allele Case frequence Control frequence χ2 p Odds ratio (95% Cl)
rs6280 DRD3 C 0,281 0,227 4,97 0,03 1,34 1.04–1.72
Chromosome 3 T 0,719 0,773 0,75 0.58–0.97
Male C 0,244 0,232 0,13 0,72 1,07 0.75–1.51
T 0,756 0,768 0,94 0.66–1.33
Female C 0,311 0,194 5,39 0,02 1,87 1.10–3.19
T 0,689 0,806 0,54 0.31–0.91
rs4680 COMT A 0,507 0,53 0,66 0,42 0,91 0.73–1.14
Chromosome 22 G 0,493 0,47 1,1 0.88–1.37
Male A 0,513 0,495 0,22 0,64 1,07 0.79–1.46
G 0,487 0,505 0,93 0.69–1.26
Female A 0,503 0,658 10,14 0,001 0,53 0.35–0.78
G 0,497 0,342 1,9 1.28–2.83
rs7322347 5HT2A A 0,419 0,314 15,01 0,0001 1,58 1.25–1.99
Chromosome 13 T 0,581 0,686 0,63 0.50–0.80
Male A 0,42 0,308 9,88 0,002 1,63 1.20–2.21
T 0,58 0,692 0,61 0.45–0.83
Female A 0,419 0,345 1,8 0,18 1,37 0.87–2.15
T 0,581 0,655 0,73 0.46–1.15