IRCT2016072511956N6.

Trial name or title	To relieve crisis pain in sickle cell anemia patients
Methods	Allocation: randomized Controlled: active comparator Blinding: double‐blind Arm: 2 parallel Centre: single Study duration: February 2017 (recruited, ongoing, data not published)
Participants	Inclusion criteria: adults with sickle cell anemia; no prior history of cardiovascular or respiratory disease; no hypertension; not using other analgesic drugs Exclusion criteria: known major side effects of trial medications; addiction, especially to morphine Baseline characteristics N: target sample size 84, recruitment complete Gender: female and male Ages: no age limit (if included, need separate adult data only) Setting and location: Emam Reza Hospital, Mashhad University of Medical Sciences, Iran
Interventions	Treatment group: 30 mg injection ketorolac Control group: 4‐10 mg injection morphine at 4 to 5 ml injection water solution
Outcomes	Primary outcomes Pain relief (VAS) 5 minutes before and 5 minutes after injection Secondary outcomes Side effects
Starting date	19 February 2017
Contact information	Somaye Sadat Hosseiny, Emam Reza Hospital, Emam Reza Square, Ebne Sina Avenue Mshhad Iran Email: somaye_2004a@yahoo.com
Notes	If study is included in future updates, need to separate adult data only