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. Author manuscript; available in PMC: 2019 Nov 19.
Published in final edited form as: Exp Neurol. 2017 Oct 19;299(Pt B):289–298. doi: 10.1016/j.expneurol.2017.10.012

Fig. 1.

Fig. 1.

Comparison of cell morphology between structures formed in 3D by wild-type SCs and NF1 PN cells. RFP variants of wild-type SCs and NF1 PN cells were established in rBM + collagen I (60:40). After six days, the live 3D cultures were imaged on confocal microscope. The images shown are tilted views of the z-stacks that have been reconstructed in 3D to show the population of multicellular structures formed. The RFP marks the volume occupied by the cells. One grid unit = 128 μm. Left panel: wild-type SC line, ipn02.8-RFP, inset: magnification of selected area; right panel: NF1 PN cell line, ipNF95.11b C/T-RFP, inset: magnification of selected area.