Table 2.
Adverse events while receiving ribociclib prior to surgery and during treatment phase
| Toxicity | Grade 1 | Grade 2 | Total |
|---|---|---|---|
| Gastrointestinal disorders | |||
| Nausea | 1 | 0 | 1 |
| General disorders and administration site conditions | |||
| Gait disturbance | 0 | 1 | 1 |
| Edema, limbs | 1 | 0 | 1 |
| Renal and urinary disorders | |||
| Creatinine increased | 0 | 1 | 1 |
| Metabolism and nutrition disorders | |||
| Hyperglycemia | 0 | 1 | 1 |
| Musculoskeletal and connective tissue disorders | |||
| Generalized muscle weakness | 0 | 1 | 1 |
| Musculoskeletal and connective tissue disorder—other: muscle pain | 1 | 0 | 1 |
| Nervous system disorders | |||
| Stroke | 1 | 0 | 1 |
| Peripheral sensory neuropathy | 1 | 0 | 1 |
| Headaches | 0 | 1 | 1 |
| Seizure | 1 | 1 | |
| Psychiatric disorders | |||
| Psychosis | 1 | 0 | 1 |
| Insomnia | 0 | 1 | 1 |
| Respiratory, thoracic and mediastinal disorders | |||
| Cough | 1 | 0 | 1 |