Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct;58:249–258. doi: 10.1016/j.sbi.2019.05.021

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Author

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

CryoSTAC of HIV-1 immature Gag particles.

(a) Tomographic slices of immature HIV-1 particles (with D25A mutation), ΔMACANCSP2 VLPs, in the absence and presence of the maturation inhibitor bevirimat (BVM). Scale bar, 50 nm. (b) CA-SP1 densities from the samples shown in (a) by subtomogram averaging. One CA-SP1 monomer is highlighted, with the CA-NTD in cyan and the CA-CTD and SP1 in orange. (c) The refined atomic model. (d) An improved CA-SP1 density map at 3.1 Å resolution by emClarity (right), compared to the previous structure (left, EMD-3782). (e) Enlarged views of boxed area in (d) overlaid with a real-space refined model [18^••,26^••].