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. 2019 Nov 20;144:124–133. doi: 10.1016/j.freeradbiomed.2019.04.020

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© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 1 — Free radical formation of 7α-HC, 7β-HC, 7-OC and 5,6-EC [34]. The reactions shown in blue boxes and by blue arrows are enzyme catalysed. CYP, cytochrome P450; HSD, hydroxysteroid dehydrogenase; ChEH, cholesterol epoxide hydrolase; LOO^., lipidperoxy radical; LO^., lipidalkoxy radical; LOH, lipidhydroxide; LOOH lipidhydroperoxide; RH, hydrogen donor.