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. 2018 Dec 4;50(1):147–155. doi: 10.1007/s42770-018-0008-3

Table 2.

Frequency and comparison of the IL28B and IFNL4 genotypes in resolving and chronically infected HCV patients

All subjects Frequency of clearance (%) Frequency of persistence (%) Comparison OR (95% CI) p value
IL28B GT CC 21 (63.6%) 10 (25.6%) 0.005*
TT 02 (6.1%) 03 (7.7%) CC vs CT + TT 0.197 (0.072–0.541) 0.001*
CT 10 (30.3%) 26 (66.7%) CT vs CC + TT 4.6 (1.697–12.469) 0.002
CT + TT 12 (36.4%) 29 (74.4%) TT vs CC + CT 1.292 (0.203–8.236) 0.786
INFL4 GT ΔG/ΔG 01 (3.7%) 07 (17.9%) ΔG/ΔG vs ΔG/TT + TT/TT 5.688 (0.657–49.231) 0.081
ΔG/TT 10 (37%) 22 (56.4%) ΔG/TT vs ΔG/ΔG + TT/TT 2.200 (0.850–6.012) 0.122
TT/TT 16 (59.3%) 10 (25.6%)†* TT/TT vs ΔG/ΔG + ΔG/TT 0.237 (0.083–0.679) 0.006*
Protective GT CC-TT/TT 13 (54.17%) 09 (23.68%) 0.015*
Deleterious GT nCC-nTT/TT 11 (45.83%) 29 (76.32%)

GT genotype. *Statistically significant. †*P = 0.014