Table 3.
Risk analysis by logistic regression, ranking the contributing factors for HCV clearance and persistence
| Risk factor ranking | OR (CI 95%*) |
|---|---|
| Protective factors for chronic | |
| IL28B CC genotype | 0.197 (0.072–0.541) |
| INFL4 TT/TT genotype | 0.237 (0.083–0.679) |
| Sex, being female is protective for chronic | 0.394 (0.159–0.977) |
| Risk factors for chronic | |
| Phthirus pubis | 15.407 (1.892–125.499) |
| IL28B CT genotype | 4.6 (1.697–12.469) |
| All sexually transmitted disease (STD) | 3.506 (1.297–9.479) |
| Condyloma acuminatum | 2.1 (1.621–2.721) |
| Herpes genital | 1.892 (1.516–2.360) |
| Other STDs | 1.816 (1.467–2.247) |
| No association | |
| Syphilis | 1.789 (0.155–20.626) |
| Haemophilus ducreyi infection | 0.821 (0.049–13.642) |
| Gonorrhea | 1.8 (0.541–5.984) |
| MSM relationship | 6.529 (0.747–57.050) |
| Number of regular partners nowadays | 1.0 (0.350–2.856) |
| Drug abuse | 0.994 (0.390–2.537) |
| Injection drug use | 2.917 (0.594–14.327) |
| Blood transfusion | 1.208 (0.407–3.583) |
| Occupational exposure | 0.559 (0.192–1.632) |
| Personal contact with drug users | 1.485 (0.429–5.143) |
| Sexual contact with drug users | 0.418 (0.135–1.299) |
| Personal contact with people with hepatitis C | 1.370 (0.286–6.559) |
| Sexual contact with people with hepatitis C | 1.667 (0.404–6.877) |
| Personal contact with people who have made blood transfusion | 1.202 (0.365–3.955) |
| Sexual contact with people who have made blood transfusion | 0.412 (0.073–2.307) |
| IL28B TT genotype | 1.292 (0.203–8.236) |
| INFL4 ∆G/∆G genotype | 5.688 (0.657–49.231) |
| INFL4 ∆G/TT genotype | 2.200 (0.805–6.012) |
OR, odds ratio; CI, confidence interval. *CI considered a p < 0.05. Data is listed accordingly to the assessment of the association. Non-exposure for each variable was used as reference for comparisons