Table 2. Deconvolution of CD138+ purified samples.
Cell Type | LM22 | LM22p5 | MGSM27 | de novo MGSM27 |
---|---|---|---|---|
B.cells.naive | 1.76 | 0.92 | 0.2 | 0 |
B.cells.memory* | 10.38 | 5.27 | 2 | 0.02 |
Plasma.cells* | 59.59 | 45.49 | 31.77 | 7.58 |
T.cells.CD8 | 1.06 | 0.13 | 0 | 0 |
T.cells.CD4.naive | 2.58 | 0.09 | 0.49 | 4.94 |
T.cells.CD4.memory.resting | 1.33 | 0.13 | 0 | 0 |
T.cells.CD4.memory.activated | 0.03 | 0.01 | 0 | 0.01 |
T.cells.follicular.helper | 5.32 | 0.36 | 0.9 | 4.74 |
T.cells.regulatory..Tregs. | 2.72 | 0.35 | 1.14 | 7.37 |
T.cells.gamma.delta | 0.03 | 0.03 | 0.06 | 6.89 |
NK.cells.resting | 0.11 | 0.09 | 0.03 | 0 |
NK.cells.activated | 0.03 | 0.01 | 0 | 0 |
Monocytes | 5.57 | 1.13 | 0.57 | 0.05 |
Macrophages.M0 | 1.36 | 0.11 | 0.03 | 0 |
Macrophages.M1 | 1.06 | 0.08 | 0.04 | 0.02 |
Macrophages.M2 | 4.14 | 0.49 | 0.52 | 0.13 |
Dendritic.cells.resting | 0.95 | 0.11 | 0.05 | 0 |
Dendritic.cells.activated | 0.57 | 0.08 | 0.06 | 0 |
Mast.cells.resting | 0.3 | 0.14 | 0.01 | 0.09 |
Mast.cells.activated | 0.06 | 0.03 | 0 | 0.01 |
Eosinophils | 0.72 | 0.21 | 0.46 | 7.24 |
Neutrophils | 0.32 | 0.29 | 0.11 | 0.01 |
others | 0 | 0 | 0 | 0 |
PlasmaMemory* | 0 | 32.56 | 24.07 | 21.76 |
MM.plasma.cell* | 0 | 4.62 | 34.51 | 29.12 |
osteoclast | 0 | 0.8 | 2.93 | 4.54 |
osteoblast | 0 | 1.1 | 0.02 | 2.93 |
adipocyte | 0 | 5.37 | 0.01 | 2.55 |
Average (mean) deconvolution reconstruction of all cell types in the 423 nearly pure CD138+ samples.
*Cell types are counted as CD138+ tumor