The frequency of fetal inflammatory response syndrome (FIRS) [a], proven early-onset neonatal sepsis (EONS) [b], suspected EONS [c] and chorioamnionitis [d] according to the progression of inflammation in UC. Each P value is shown in graph. Of 239 cases which met the entry for this study, 215 patients had UCP CRP concentrations at birth; however, 24 patients did not have an UCP CRP concentration at birth because of the limited amount of the remaining UCP, and therefore, we could not examine the frequency of FIRS. Moreover, twenty-three neonates were excluded from the analysis in the evaluation of proven EONS and suspected EONS because they died shortly after delivery as a result of extremely prematurity (n = 19) or anomaly (n = 4) and thus could not be evaluated with respect to the presence or absence of proven EONS and suspected EONS.