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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2019 Oct 21;1866(1):165560. doi: 10.1016/j.bbadis.2019.165560

Figure 1. Elevated levels of ATX in the AH of POAG patients.

Figure 1.

A). Demographic details of the study population. B). ATX protein levels were significantly elevated in the AH of POAG patients (n = 27) compared to cataract (control) patients (n = 27) based on Mann Whitney U test. C). The ATX protein levels in AH samples and preoperative IOP values POAG patients were significantly and positively correlated (Pearson Correlation Coefficient = 0.622, 95% confidence interval = 0.316 to 0.810, p≤0.001). D). ATX protein levels in the AH of POAG patients was significantly elevated in both males (n = 9) and females (n = 18) compared to cataract patients (males, n = 13; females, n = 13) by the multiple t-test. Within the POAG group however, the ATX protein levels did not differ between males and females. E). AH ATX protein levels were significantly elevated in the Caucasian (n = 14) and African American POAG patients (n = 13) compared to cataract patients (Caucasian, n = 22 and African American, n = 3) based on the Multiple t-test. F). No correlation was found between patient age and AH ATX protein level in the POAG group (Pearson Correlation Coefficient = 0.231, 95% CI = 0.562 to 0.164, p = 0.247). Individual dots represent results for individual patients/subjects. Black dots = cataract subjects. Blue dots = POAG patients. Data in panels B, D and E represent the median and interquartile range. Data in C and F panels represent the mean linear regression (black line) and the 95% confidence interval (black dotted line).