Table 1.

Clinical and demographical features of no-TRD and TRD patients.

Characteristics	no-TRD (n = 247)	TRD (n = 380)	p-value
Age (years), mean (SD)	54·0 (14·6)	56·7 (13·3)	0·02
Gender (% female)	71·3	66·6	0·22
Education (years), mean (SD)	10·0 (4·0)	8·9 (3·9)	0·001
% of recurrent MDD	69·4	90·5	<0·001
% of severe vs. moderate MDD	42·1	87·4	<0·001
% psychotic symptoms	3·7	35·0	<0·001
% comorbidity with personality disorders	14·0	26·7	<0·001
% comorbidity with anxiety disorders	38·9	43·7	0·23
% comorbidity with alcohol abuse	4·8	3·2	0·34

SD, standard deviation.