Table 1.

Access to innovative medicines for metastatic melanoma and economic and healthcare system parameters39

	Number of reimbursed medicines	Delay in reimbursement	Restrictions in reimbursement	GDP*	Human development index	HEPC	Mackenbach score	HTA	Type of reimbursement
Europe
Austria	8	185.5	No	50 078	0.885	5138	48	Yes	Discount rebates
Belgium	8	355	Yes	46 383	0.89	4782	17	Yes	Price cap freezes
Denmark	8	357	Yes	49 496	0.923	5083	43	Yes	Price volume agreements
France	7	543.5	No	41 466	0.888	4542	52	Yes	Price volume agreements
Germany	9	30	No	48 730	0.916	5357	35	Yes	Discount rebates
Greece	8	451.5	No	26 783	0.865	2204	16	Yes	Discount rebates
Ireland	6	636	No	68 883	0.923	5335	38	Yes	Discount rebates
Italy	6	724	No	38 161	0.873	3351	31	Yes	Discount rebates
Portugal	2	1057.5	Yes	30 624	0.83	2661	19	Yes	Not known
Spain	7	977.5	No	36 310	0.876	3183	35	No	Discount rebates
Switzerland	8	0	No	62 882	0.93	7583	46	No	Not known
UK	7	395.5	No	42 609	0.747	4145	37	Yes	Discount rebates
Albania	2	1314	No	11 929	0.733	774	−13	No	Not known
Belarus	1	1314	Yes	18 060	0.798	1085	−25	Yes	Not known
Bosnia and Herzegovina	0	1458	No	12 075	0.733	1102	−60	Yes	Not known
Bulgaria	3	996	No	19 199	0.782	1492	−33	No	MEA
Croatia	5	938	Yes	23 596	0.818	1656	−17	No	MEA
Czech Republic	5	801.5	Yes	34 711	0.87	2470	12	Yes	MEA
Estonia	3	1149.5	No	29 365	0.861	1887	−32	Yes	MEA
Lithuania	2	1367.5	No	29 966	0.839	1875	−28	Yes	MEA
FYR Macedonia	2	933.5		15 121	0.747	857	0	Yes	Price cap freezes
Montenegro	3	1303	Yes	16 854	0.802	957	−18	No	Not known
Poland	7	501.5	No	27 811	0.843	1704	-4	Yes	Price volume agreements
Romania	4	905.5	No	23 626	0.793	1090	−42	Yes	Price volume agreements
Serbia	3	1130.5	Yes	14 512	0.771	1324	−17	Yes	MEA
Slovenia	7	631	No	32 885	0.88	2734	15	No	Discount rebates
Ukraine	1	1274.5	No	8272	0.907	469	−73	No	Not known

*GDP, gross domestic product, World Bank Data.

HEPC, health expenditure per capita; HTA, health technology assessment; MEA, managed entry agreements.