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Mice serum levels of alkaline phosphatase (ALP), blood urea nitrogen (BUN), creatinine, and bilirubin. Mice (n=6) were intranasally immunized with either saline, porcine reproductive and respiratory syndrome virus (PRRSV) antigen-only or antigen admixed with 10, 50, or 100 µg rLTB, on days 0, 7, and 21. Sera were collected on days 2 and 28, and ALP (A), BUN (B), creatinine (C), and bilirubin (D) levels detected. Data are expressed as mean ± SD. ***P<0.001 versus the saline group.
