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. 2019 Nov 19;9:17096. doi: 10.1038/s41598-019-52764-8

Table 12.

Interacting amino acids with Synthetic UDP-furanoses as GlfT2 inhibitors.

Compounds Major interacting amino acids Additional interacting amino acids
Natural substrate Y236 D256 W309 W348 K369 D372 W399 Q409
49 Y236 D256 W348 P167 G232 W347 I368 F169 D371 T168
50 Y236 W348 D372 P167 R171 G232 D371
51 Y236 D256 W348 K369 D372 P167 G232 W347 I368 D371 T168
52 Y236 D256 W348 K369 D372 P167 G232 W347 I368 D371 T168