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. 2019 Nov 19;9:17096. doi: 10.1038/s41598-019-52764-8

Table 14.

Interacting amino acids with Synthetic Acceptor Substrates as GlfT2 inhibitors.

Com-pounds Major interacting amino acids Additional interacting amino acids
Natural substrate Y236 D256 W309 W348 K369 D372 W399 Q409
53 Y236 D256 W348 D372 P167 G232 W347 I368 F169 D371 G231 Q200 N229
54 Y236 D256 K369 D372 P167 G232 W347 I368 F169 D371 T168 G231 H396
55 Y236 D256 W348 K369 P167 R171 G232 W347 I368 F169 D371 W408
56 Y236 D256 W348 K369 D372 P167 G232 W347 I368 G231 W408