Table 26.

Predicted activity of the top hit compounds on toxicity endpoints.

Compound	Hepatotoxicity	Carcinogenicity	Immunotoxicity	Mutagenicity	Cytotoxicity
1	Inactive	Inactive	Active	Inactive	Inactive
2	Inactive	Inactive	Active	Inactive	Inactive
3	Inactive	Inactive	Active	Inactive	Inactive
4	Inactive	Inactive	Active	Active	Inactive
27	Inactive	Inactive	Active	Inactive	Inactive
31	Inactive	Inactive	Inactive	Inactive	Inactive
58	Inactive	Inactive	Active	Inactive	Inactive
59	Inactive	Inactive	Active	Inactive	Inactive
60	Inactive	Inactive	Active	Inactive	Inactive
61	Inactive	Inactive	Active	Inactive	Inactive
62	Inactive	Inactive	Active	Inactive	Inactive
63	Inactive	Inactive	Active	Inactive	Inactive
64	Inactive	Inactive	Active	Inactive	Inactive
65	Inactive	Inactive	Active	Inactive	Inactive
66	Inactive	Inactive	Active	Inactive	Inactive
67	Inactive	Inactive	Active	Inactive	Inactive
68	Inactive	Inactive	Active	Inactive	Inactive
69	Inactive	Inactive	Active	Inactive	Inactive
70	Inactive	Inactive	Active	Inactive	Inactive
71	Inactive	Inactive	Active	Inactive	Inactive
72	Inactive	Inactive	Active	Inactive	Inactive
73	Inactive	Inactive	Active	Inactive	Inactive
74	Inactive	Inactive	Active	Inactive	Inactive
75	Inactive	Inactive	Active	Inactive	Inactive