Table 3.

Binding affinities and Inhibition constant (T = 298.15 K) of Imino-Sugars as GlfT2 inhibitors.

Compounds	Binding energy (kcal/mol)	Inhibition constant, µM
Natural substrate	−6.63 ± 0.02	14
14	−4.18 ± 0.01	856
15	−6.69 ± 0.01	12
16	−6.83 ± 0.01	10
17	−6.36 ± 0.01	21
18	−5.02 ± 0.01	209
19	−6.72 ± 0.01	12