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. 2019 Nov 19;9:17055. doi: 10.1038/s41598-019-53062-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Dynamics of Zika virus spread considering two sexes and involving vectorial and sexual transmission. Male and female human and vector populations are differentiated by the subscripts $m$ , $f$ , $v$ , respectively. Red nodes are infectious and brown nodes are non-infectious. Black solid arrows show the progression of infection. Blue dashed arrows show male-to-female human transmission. Red dash-dotted lines show human-to-mosquito transmission and red dotted lines show mosquito-to-human transmission. Green arrows show natural birth.