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. 2019 Nov 13;6:124. doi: 10.3389/fmolb.2019.00124

Figure 1.

Figure 1

Molecular models of the main steps of lipid droplet biogenesis. Neutral lipids are produced and stored between the two leaflets of the endoplasmic reticulum bilayer (A) and they aggregate in lenses (B) that grow into nascent lipid droplets (C). Subsequently, lipid droplets bud from the bilayer (D) and they can either stay connected to the endoplasmic reticulum (E) or detach in the cytosol (E,F). Images are snapshots from molecular dynamics simulations. NL: orange; PL polar heads: gray; PL acyl chains: yellow.