Table 1.
Relationship between demographic, clinical characteristics and MCA with and without additional infarct.
| Factors | Total (n = 137) | Subtotal MCA (n = 28) | Co MCA (n = 52) | Subtotal MCAAI (n = 25) | Co MCAAI (n = 32) | P-value |
|---|---|---|---|---|---|---|
| Age | 47.88 ± 11.00 | 45.14 ± 10.99 | 47.88 ± 10.30 | 48.28 ± 8.06 | 49.97 ± 13.76 | 0.236 |
| <55years | 104(75.9%) | 25(89.3) | 41(78.8) | 20(80.0) | 18(56.3) | 0.019 |
| ≥ 55 years | 33(24.1%) | 3(10.7) | 11(21.2) | 5(20.0) | 14(43.8) | |
| Gender | 0.313 | |||||
| Male | 111 (81.0%) | 24(85.7) | 38(73.1)) | 22(88.0) | 27(84.4) | |
| Female | 26 (19.0) | 4 (14.3) | 14 (26.9) | 3(12.0) | 5(15.6) | |
| Risk Factors | ||||||
| Hypertension | 63 (46.0) | 15 (53.6) | 19 (36.5) | 13(52.0) | 16(50.0) | 0.378 |
| Diabetes | 47 (34.3) | 10 (35.7) | 14 (26.9) | 7(28.0) | 16(50.0) | 0.156 |
| Dyslipidemia | 50 (36.5) | 9 (32.1) | 20 (38.5) | 9(36.0) | 12(37.5) | 0.954 |
| CAD | 30 (21.9) | 5 (17.9) | 10 (19.2) | 6(24.0) | 9(28.1) | 0.735 |
| Atrial Fibrillation | 13 (9.5) | 3 (10.7) | 2 (3.8) | 4(16.0) | 4(12.5) | 0.315 |
| CHF | 12 (8.8) | 2 (7.1) | 3 (5.8) | 3(12.0) | 4(12.5) | 0.668 |
| Arrival Time (hours) | 4.49 ± 5.38 | 4.52 ± 5.23 | 5.52 ± 6.38 | 4.17 ± 5.47 | 3.05 ± 2.97 | 0.482 |
| Uncal Herniation on CT | 92(67.2) | 2(7.1) | 52(100.0) | 6(24.0) | 32(100.0) | <0.001 |
| Subfalcine Herniation on CT | 39(28.5) | 6(21.4) | 14(26.9) | 7(28.0) | 12(37.5) | 0.567 |
| Comatose | 83(60.6) | 17(60.7) | 32(61.5) | 14(56.0) | 20(62.5) | 0.962 |
| Pupillary abnormality | 27(19.7) | 2(7.1) | 10(19.2) | 4(16.0) | 11(34.4) | 0.061 |
| Bilateral Babinski | 83(60.6) | 15(53.6) | 33(63.5) | 15(60.0) | 20(62.5) | 0.847 |
| Herniation time from onset | 0.009 | |||||
| <24 hours | 29(21.2) | 1(3.6) | 14(26.9) | 4(16.0) | 10(31.3) | |
| 24-<48 hours | 51(37.2) | 6(21.4) | 18(34.6) | 14(56.0) | 13(40.6) | |
| 48-<72 hours | 30(21.9) | 11(39.3) | 12(23.1) | 3(12.0) | 4(12.5) | |
| ≥72 hours | 27(19.7) | 10(35.7) | 8(15.4) | 4(16.0) | 5(15.6) | |
| SP displacement last CT ≥ 1 cm | 81(59.1) | 16(57.1) | 28(53.8) | 15(60.0) | 22(68.8) | 0.598 |
| CT time to MIV (hr.) | 58.06 ± 55.79 | 85.58 ± 84.96 | 48.44 ± 32.40 | 47.25 ± 31.90 | 58.05 ± 62.60 | 0.044 |
| MIV (cm3) | 367.7 ± 119.44 | 304.9 ± 97.15 | 367.7 ± 113.7 | 347.6 ± 110.5 | 438.2 ± 120.9 | <0.001 |
| DHC Time | ||||||
| ≤48 hours | 54 (39.4%) | 3(10.7%) | 21(40.4%) | 11(44.0) | 19(59.4) | 0.002 |
| >48 hours | 83 (60.6%) | 25(89.3%) | 31(59.6%) | 14(56.0) | 13(40.6) | |
| Centers involved | ||||||
| Doha- Qatar | Dubai-UAE | 88[64.2%] | 18 [63.45%] | 34[65.4%] | 18[72.0%] | 18[56.3%] |
| Doha- Qatar | 39[28.5%] | 8 [28.6%] | 12[23.1%] | 6[24.0%] | 13[40.6%] | |
| I Islamabad-Pakistan | 10[7.37] | 2 [7.1%] | 6[11.5%] | 1[4.0%] | 1[3.1%] | |
| Prognosis at three month | ||||||
| Favorable (mRS0–3) | 34(24.8) | 14(50.0) | 19(36.5) | 1(4.0) | 0 | <0.001 |
| Unfavorable (mRS 4–6) | 103|(75.2) | 14(50.0) | 33(63.5) | 24(96.0) | 32(100.0) | |
| Favorable (mRS0–4) | 84(61.3) | 28(100.0) | 35(67.3) | 11(44.0) | 10(31.3) | <0.001 |
| Unfavorable (mRS 5–6) | 53|(38.7) | 0 | 17(32.7) | 14(56.0) | 22(68.8) | |
| 30 Day Mortality | 23(16.8) | 0 | 4(7.7) | 8(32.0) | 11(34.4) | <0.001 |
Results are expressed as mean ± standard deviation, Median (Inter Quartile Range), and number (percentage), Median (Inter Quartile Range), and number (percentage). MIV Maximum Infarct Volume, SP septum pellucidum.