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. 2019 Nov 13;10:2638. doi: 10.3389/fimmu.2019.02638

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Copyright © 2019 Fu, Jiang, Hao, Liu, Ding, Zhang, Yang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of signal transducer and activator of transcription 6 (STAT6) in CD11b⁺ cells in interstitial cells of carcinoma tissue. (A) Immunohistochemical (IHC) staining of CD11b in para-carcinoma and carcinoma tissues of lung cancer patients. Bars represent 2 mm, 500 μm, and 200 μm, respectively. The same magnification is shown in the same column of images. Representative figure of pulmonary adenocarcinoma in the lung cancer patients was shown in Supplementary Figure 5. (B) IHC score of CD11b in tissue microarrays of carcinoma and para-carcinoma in patients with lung cancer. (C) IHC staining of STAT6 in para-carcinoma and carcinoma tissues of lung cancer patients. Bars represent 2 mm, 500 μm, and 200 μm, respectively. The same magnification is shown in the same column of images. (D) IHC score of STAT6 in tissue microarrays of carcinoma and para-carcinoma in 36 patients with lung cancer. (E) Confocal scanning of STAT6 and CD11b expression in human lung tissue. Unpaired Student's t-tests were used unless noted otherwise. ^**P < 0.01, ^***P < 0.001.