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. 2019 Nov 13;13:59. doi: 10.3389/fnsys.2019.00059

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Copyright © 2019 Bensaid, Modolo, Merlet, Wendling and Benquet.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Simulated vs. Real EEG during wakefulness and SWS. Signals simulated with the whole-brain model using weak thalamo-cortical connectivity parameters (A) display background activity. The morphology and spectral content of these simulated signals are similar to scalp EEG recorded in a human subject during wakefulness in humans (C), except for a higher power spectral density in the beta sub-band. Signals simulated with the whole-brain model using strong thalamo-cortical connectivity parameters (B) display delta waves similar to the activity recorded in real condition during SWS in humans (D). The spectral content of signals as well as the topographical voltage distribution at the peak of delta waves were similar in the simulated and real conditions.