Table 2.
Antioxidant | Unadjusted analysis | Adjusted analysis† | ||||
---|---|---|---|---|---|---|
β* | 95% confidence intervals | P | β* | 95% confidence intervals | P | |
Retinol (μmmol/L) | −1.363 | −2.595, −0.131 | 0.03 | −1.436 | −2.598, −0.274 | 0.02 |
γ-Tocopherol (μmmol/L) | −0.069 | −0.437, −0.299 | 0.71 | −0.035 | −0.398, 0.329 | 0.85 |
α-Tocopherol (μmmol/L) | 0.013 | −0.078, 0.103 | 0.79 | 0.048 | −0.041, 0.136 | 0.29 |
Lutein (mmol/L) | 0.050 | 0.023, 0.077 | <0.01 | 0.041 | 0.015, 0.068 | <0.01 |
Zeaxanthin (mmol/L) | 0.123 | 0.012, 0.235 | 0.03 | 0.097 | −0.014, 0.207 | 0.09 |
β−Cryptoxanthin (mmol/L) | 0.030 | −0.029, 0.089 | 0.32 | 0.048 | −0.012, 0.107 | 0.12 |
α-Carotene (mmol/L) | 0.019 | −0.026, 0.065 | 0.41 | 0.028 | −0.020, 0.075 | 0.25 |
β-Carotene (mmol/L) | 0.005 | −0.003, 0.014 | 0.21 | 0.008 | 0.000, 0.017 | 0.05 |
Lycopene (μmmol/L) | 0.048 | −1.622, 1.718 | 0.96 | 0.145 | −1.637, 1.927 | 0.87 |
*Average increase in each serum antioxidant level per unit increase in eGFR.
†Multiple regression analysis adjusted for age (years), gender, smoking (pack-years), the number of APOE4 alleles and Alzheimer’s disease status.