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. 2019 Nov 19;9:17068. doi: 10.1038/s41598-019-53674-5

Table 2.

Association of serum antioxidants with eGFR in all study participants.

Antioxidant Unadjusted analysis Adjusted analysis
β* 95% confidence intervals P β* 95% confidence intervals P
Retinol (μmmol/L) −1.363 −2.595, −0.131 0.03 −1.436 −2.598, −0.274 0.02
γ-Tocopherol (μmmol/L) −0.069 −0.437, −0.299 0.71 −0.035 −0.398, 0.329 0.85
α-Tocopherol (μmmol/L) 0.013 −0.078, 0.103 0.79 0.048 −0.041, 0.136 0.29
Lutein (mmol/L) 0.050 0.023, 0.077 <0.01 0.041 0.015, 0.068 <0.01
Zeaxanthin (mmol/L) 0.123 0.012, 0.235 0.03 0.097 −0.014, 0.207 0.09
β−Cryptoxanthin (mmol/L) 0.030 −0.029, 0.089 0.32 0.048 −0.012, 0.107 0.12
α-Carotene (mmol/L) 0.019 −0.026, 0.065 0.41 0.028 −0.020, 0.075 0.25
β-Carotene (mmol/L) 0.005 −0.003, 0.014 0.21 0.008 0.000, 0.017 0.05
Lycopene (μmmol/L) 0.048 −1.622, 1.718 0.96 0.145 −1.637, 1.927 0.87

*Average increase in each serum antioxidant level per unit increase in eGFR.

Multiple regression analysis adjusted for age (years), gender, smoking (pack-years), the number of APOE4 alleles and Alzheimer’s disease status.