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. 2019 Nov 19;9:17048. doi: 10.1038/s41598-019-52798-y

Table 2.

Participants’ socio-demographic characteristics (n = 10,598) .

20–34 years (n = 1,889) p value 35–49 years (n = 8,709) p value
All Anemia Without anemia All Anemia Without anemia
n = 263 n = 1,626 n = 1,548 n = 7,161
13.9% 86.1% 17.8% 82.2%
Median (IQRa) or N (%) or Mean ± SD Median (IQRa) or N (%) or Mean ± SD
Age (years) 30.0 (26.0–32.0) 30.0 (26.0–32.0) 30.0 (26.0–32.0) 0.729b 44.0 (40.0–47.0) 44.0 (41.0–47.0) 44.0 (40.0–47.0) 0.008b
Body mass index (kg/m2) 0.445c 0.051c
less than 18.5 402 (21.3) 48 (18.3) 354 (21.7) 1,503 (17.3) 262 (16.9) 1,241 (17.3)
18.5–24.9 1,375 (72.8) 201 (76.4) 1,174 (72.2) 6,308 (72.4) 1,154 (74.5) 5,154 (72.0)
25.0–29.9 96 (5.1) 13 (4.9) 83 (5.1) 720 (8.3) 102 (6.6) 618 (8.6)
30.0 or more 16 (0.8) 1 (0.4) 15 (0.9) 177 (2.0) 30 (1.9) 147 (2.1)
Weight change over the past year 0.067c 0.021c
No change 1,384 (73.3) 208 (79.1) 1,176 (72.3) 6,532 (75.0) 1,203 (77.7) 5,329 (74.4)
3 kg or more increase 343 (18.2) 39 (14.8) 304 (18.6) 1,750 (20.1) 273 (17.6) 1,477 (20.6)
3 kg or more decrease 161 (8.5) 16 (6.0) 145 (8.4) 427 (4.9) 72 (4.7) 355 (5.0)
Current medical history
Adenomyosis 8 (0.4) 0 (0.0) 8 (0.5) 0.301d 127 (1.5) 30 (1.9) 97 (1.4) 0.082c
Endometriosis enterna (e.g. chocolate cyst, endometriosis cyst) 30 (1.6) 2 (0.8) 28 (1.7) 0.190d 241 (2.8) 40 (2.6) 201 (2.8) 0.628c
Uterine myoma 20 (1.1) 4 (1.5) 16 (1.0) 0.300d 827 (3.5) 202 (13.0) 625 (8.7) <0.001c
Cervical cancer 2 (0.1) 1 (0.4) 1 (0.1) 0.259d 48 (0.6) 7 (0.5) 41 (0.6) 0.562c
Endometrial cancer 1 (0.1) 0 (0.0) 1 (0.1) 0.861d 13 (0.1) 1 (0.1) 12 (0.2) 0.299d
Ovarian tumor (malignant/benign) 10 (0.5) 2 (0.8) 8 (0.5) 0.416d 122 (1.4) 20 (1.3) 102 (1.4) 0.688c
Abnormality of uterine cytology 35 (1.9) 5 (1.9) 30 (1.8) 0.550d 315 (3.6) 47 (3.0) 268 (3.7) 0.177c
Breast cancer/mastopathy 9 (0.5) 1 (0.4) 8 (0.5) 0.637d 374 (4.3) 66 (4.3) 308 (4.3) 0.947c
Gastric ulcer 0 0 0 5 (0.1) 2 (0.1) 3 (0.0) 0.218d
Duodenal ulcer 0 0 0 5 (0.1) 3 (0.2) 2 (0.0) 0.042d
Ulcerative colitis 3 (0.2) 1 (0.4) 2 (0.1) 0.362d 25 (0.3) 7 (0.5) 18 (0.3) 0.141d
Body fat percentage 24.8 ± 5.6 24.1 ± 5.2 25.0 ± 5.6 0.026e 25.8 ± 6.33 24.8 ± 5.8 26.0 ± 6.4 <0.001 f
Smoking habits 0.245c <0.001c
Non-smoker 1,689 (89.5) 243 (92.3) 1,446 (88.9) 7,110 (81.6) 1,340 (86.6) 5,770 (80.6)
Current smoker 47 (2.5) 5 (1.9) 42 (2.6) 422 (4.8) 58 (3.7) 364 (5.1)
Smoked in the past 152 (8.1) 15 (5.7) 137 (8.4) 1,177 (13.5) 150 (9.7) 1,027 (14.3)
Number of tobacco per day 8.0 (5.0–12.0) 8.0 (5.0–10.0) 8.0 (4.0–12.0) 0.825b 10.0 (5.0–15.0) 10.0 (5.0–10.0) 10.0 (5.0–15.0) 0.119b
Drinking habits 0.015c <0.001c
Non-drinker 1,058 (56.0) 169 (64.3) 889 (54.7) 4,195 (48.2) 813 (52.5) 3,382 (47.2)
Occasional drinker 306 (16.2) 36 (13.6) 270 (16.6) 1,464 (16.8) 289 (18.7) 1,175 (16.4)
Habitual drinker 524 (27.8) 58 (22.1) 466 (28.7) 3,050 (35.0) 446 (28.8) 2,604 (36.4)
Number of days per week with alcohol consumption 2.0 (1.0–4.0) 2.0 (1.0–3.25) 2.0 (1.0–4.0) 0.149b 3.0 (1.0–5.0) 2.0 (1.0–5.0) 3.0 (1.0–5.0) 0.001b
Sleeping habits 0.152c 0.072c
7 hours or more 299 (29.3) 36 (13.6) 263 (16.2) 1,273 (24.5) 205 (22.2) 1,068 (25.0)
6 hours or below 722 (70.7) 112 (42.5) 610 (37.5) 3,913 (75.5) 717 (77.8) 3,196 (75.0)
Exercise habits (light exercise, including walking for more than 20 minutes) 0.892c 0.284c
No exercise 837 (44.3) 113 (42.9) 724 (44.5) 3,509 (40.3) 655 (42.3) 2,854 (39.9)
Exercising 1–2 days per week 677 (35.9) 97 (36.8) 580 (35.7) 3,250 (37.3) 557 (36.0) 2,693 (37.6)
Exercising 3–5 days per week 240 (12.7) 36 (13.6) 204 (12.5) 1,370 (15.7) 242 (15.6) 1,128 (15.8)
Exercising almost every day 134 (7.1) 17 (6.4) 117 (7.2) 580 (6.7) 94 (6.1) 486 (6.8)

a: IQR = interquartile range (25th – 75th percentile), b: Mann-Whitney U test, c: Chi-square test, d: Fisher’s exact test, e: Student’s t-test, f: Welch’s t-test.

Anemia: Hb < 12.0 g/dL

Without anemia: Hb ≥ 12.0 g/dL

20–34 years: n = 1,888 for Weight change over the past year, Smoking habits, Drinking habits, Exercise habits. n = 1,886 for Body fat percentage. n = 199 for Number of tobacco per day. n = 830 for Number of days per week with alcohol consumption. n = 1,021 for Sleeping habits.

35–49 years: n = 8,708 for Body Mass Index. n = 8,706 for Body fat percentage. n = 1,599 for Number of tobacco per day. n = 4,514 for Number of days per week with alcohol consumption. n = 5,186 for Sleeping habits.