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. 2019 Nov 19;9:16324. doi: 10.1038/s41598-019-51974-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Time-averaged EEG results. (A) The comparison of DMT versus placebo for changes in spectral activity reveals significant decreases for the alpha and beta bands for conventional spectral power. The decomposed spectra into oscillatory and fractal power, revealed similar results for the former and reductions were seen on all bands < 30 Hz for the latter. Filled circles correspond to clusters p < 0.01 and hollow circles for clusters p < 0.05, N = 12. (B) Grand-average spectral power for DMT and placebo corresponding to spectral, oscillatory and fractal (1/f) components of the signal (N = 12). (C) Increases are seen for both measures of spontaneous signal diversity following DMT administration compared to placebo Filled circles correspond to clusters p < 0.01 and hollow circles for clusters p < 0.05, N = 12 (LZs = Lempel-Ziv complexity, LZs_N = normalized LZs).