Table 3.

Case control studies about the role of emotional stressors on the clinical course of GD.

Author (year)	Relationship	Study method	Subjects (Number; Male, Female)	Period of stress evaluation/Thyroid status at the time of study
Yoshiuchi et al. (1998) [56]	Yes	Questionnaire Prospective	Graves’ disease (230; M48, F182)	1 year after treatment
Fukao et al. (2003) [57]	Yes	Questionnaire Prospective	Graves’ disease (69; M4, F65) Control (32; M1, F31)	1 year after the cessation of ATD/Euthyroid after 2–5 years treatment
Vita et al. (2014) [58]	Yes	Interview Retrospective	Graves’ disease (58; M22, F36)	After ATD treatment for 1–5 years