Table 4.

Case control studies about the role of personalities and psychological states on the clinical course of GD.

Author (year)	Relationship	Study method	Subjects (Number; Male, Female)	Period of prognosis evaluation/Personality evaluated
Fukao et al. (2002) [59]	Yes	Questionnaire Prospective	Graves’ disease (73; M11, F62)	3 years after ATD treatment Ego state, depression, alexithymia
Fukao et al. (2003) [57]	Yes	Questionnaire Prospective	Graves’ disease (69; M4, F65) Control (32; M1, F31)	1 year after the cessation of ATD treatment hypochondriasis, depression, psychasthenia
Fukao et al. (2011) [60]	Yes	Questionnaire Prospective	Graves’ disease (48; M6, F42)	4 years after ATD treatment hypochondriasis, depression, psychasthenia