Table 2:
Univariate analysis of variables comparing recipients with and without incident PVT at the time of liver transplantation
| Incident PVT (n=4,311) | No Incident PVT (n=62,254) | p-value | |
|---|---|---|---|
| African American, n (%) | 260 (6.3) | 5856 (9.4) | <0.001 |
| Age, years, mean (95% CI) | 55.3 (55.0–55.6) | 54.0 (53.9–54.1) | <0.001 |
| Diabetes, n (%) | 1360 (31.5) | 15476 (24.9) | <0.001 |
| HCC, n (%) | 958 (22.2) | 14934 (24.0) | 0.01 |
| HCV, n (%) | 1066 (24.7) | 18212 (29.3) | <0.001 |
| Hispanic, n (%) | 671 (15.6) | 8014 (12.9) | <0.001 |
| MELD, mean (95% CI) | 17.3 (17.1–17.6) | 18.1 (18.0–18.2) | <0.001 |
| Moderate-severe ascites, n (%) | 1427 (33.1) | 18010 (28.9) | <0.001 |
| NASH, n (%) | 751 (17.4) | 7693 (12.4) | <0.001 |
| TIPS, n (%) | 587 (13.6) | 6253 (10.0) | <0.001 |
Hepatitis C; MELD=Model for End Stage Liver Disease; NASH=Nonalcoholic Steatohepatitis; PVT=Portal Vein Thrombosis; TIPS=Transjugular Intrahepatic Portosystemic Shunt
The proportion of NASH was greater among total candidates with incident PVT while HCV was less frequent. Race and ethnicity were important as well with greater rates of PVT in Hispanics and lower rates in Blacks.