Table 1.
Demographics and Substance Use Characteristics
| CU (n=50) M (SD) range |
MCU (n=68) M (SD) range |
|
|---|---|---|
| Age, Baseline* | 13.70 (.69) 12.39–15.07 |
13.32 (.68) 12.13–14.71 |
| Age, Follow-Up | 22.11 (2.01) 16.11–26.84 |
22.30 (2.06) 14.40–26.52 |
| Est. IQ (WRAT-3), Baseline | 111.54 (10.26) 80–132 |
112.50 (10.02) 83–132 |
| % Female | 66% | 50% |
| % Hispanic | 24% | 24% |
| % Caucasian | 64% | 69% |
| Total length of follow-up interval in years | 8.41 (2.00) 2.99–12.02 |
8.98 (1.86) 1.98–13.14 |
| Number of follow-up visits | 9.02 (2.05) 4–13 |
9.65 (1.73) 4–13 |
| BDI, Baseline | 1.26 (2.28) 0–9 |
1.28 (2.47) 0–15 |
| Family History of SUD/AUD | .23 (.28) 0–1 |
.17 (.29) 0–1 |
| Cannabis use episodes, Baseline | -- | -- |
| Lifetime cannabis use episodes, Follow-Up* | 624.18 (555.44) 50–2518 |
5.24 (8.78) 0–39 |
| Past year cannabis use episodes, Follow-Up* | 197.20 (114.66) 50–381 |
.59 (1.11) 0–4 |
| % CUD Diagnosis, Follow-Up | 6% | -- |
| Age of Onset of Regular Cannabis Use | 18.78 (1.90) 15–23 |
-- |
| Length of Regular Cannabis Use, Years | 3.33 (2.09) .04–8.64 |
-- |
| Alcohol use days, Baseline | .08 (.40) 0–2 |
.02 (.12) 0–1 |
| Lifetime alcohol use days, Follow-Up* | 437.88 (354.80) 40–1427 |
170.43 (243.92) 0–1113 |
| Past year alcohol use days, Follow-Up* | 118.80 (100.95) 7–443 |
57.04 (71.29) 0–337 |
| Past year binge episodes, Follow-Up* | 27.70 (48.37) 0–206 |
6.00 (11.92) 0–72 |
| Lifetime other drug Use, Follow-Up* | 13.50 (15.79) 0–49 |
0.87 (3.09) 0–19 |
| Left Lateral OFC Volume | 9498.18 (1089.36) 7317–11361 |
9136.40 (1128.65) 6946–11423 |
| Right Lateral OFC Volume | 9640.84 (1230.05) 6287–11400 |
9378.12 (1187.16) 6785–12458 |
| Left Medial OFC Volume | 6384 (1139.00) 4608–8754 |
6407.78 (958.78) 4587–8790 |
| Right Medial OFC Volume | 6370.28 (861.95) 4635–8493 |
6338.26 (683.23) 5179–8239 |
| Left Lateral OFC Cortical Thickness | 2.80 (.18) 2.39–3.15 |
2.77 (.18) 2.32–3.10 |
| Right Lateral OFC Cortical Thickness | 2.83 (.22) 2.19–3.33 |
2.81 (.16) 2.42–3.18 |
| Left Medial OFC Cortical Thickness | 2.73 (.19) 2.22–3.06 |
2.74 (.17) 2.38–3.27 |
| Right Medial OFC Cortical Thickness | 2.72 (.21) 2.18–3.08 |
2.73 (.17) 2.34–3.18 |
| Left Lateral OFC Surface Area | 2867.94 (325.99) 2169–3382 |
2777.13 (316.04) 2099–3478 |
| Right Lateral OFC Surface Area | 2938.92 (329.38) 2263–3383 |
2870.28 (330.56) 2193–3682 |
| Left Medial OFC Surface Area | 1966.020 (344.28) 1506–2661 |
1961.50 (286.80) 1329–2716 |
| Right Medial OFC Surface Area | 1945.36 (275.00) 1418–2618 |
1945.35 (248.55) 1529–2658 |
Notes:
*
p<.05
CU=Cannabis Users; MCU=Minimal Cannabis User; OFC=Orbitofrontal Cortex; BDI=Beck Depression Inventory; SUD=Substance Use Disorder; AUD=Alcohol Use Disorder; CUD=Cannabis Use Disorder; Regular Cannabis Use is defined as weekly cannabis use